At CHAM, pediatric investigators are making breakthrough scientific discoveries to advance child health and prevent and treat devastating childhood diseases. As the Pediatric Hospital for the Albert Einstein College of Medicine (Einstein), one of the nation’s premier biomedical research institutions, CHAM provides a collaborative environment where multidisciplinary research is the norm and where cutting edge technology is applied to the healthcare challenges facing our nation’s children.
Backed by a total grant portfolio exceeding $36 million in 2014, CHAM investigators are pioneering new approaches and therapies to prevent and treat chronic pediatric conditions, such as asthma, obesity, autism and sickle cell disease as well as life-threatening diseases of childhood, including cancer, neonatal lung diseases and infectious diseases. CHAM investigators are engaged in the full spectrum of pediatric research from basic genetic, biochemical and immune mechanisms of disease to clinical/translational research to health services research, comparative effectiveness research and quality and process improvement science. Our efforts have led to the development of new treatments for childhood diseases, new and safer models of healthcare delivery and improved outcomes and quality of life for the children we serve at CHAM and around the globe.
The diversity and excellence of our research underscore CHAM’s dedication to improving child health across a wide range of disciplines and diseases. With particular strengths in understanding and addressing disparities in health care delivery and outcomes for economically disadvantaged and under-represented children, research conducted at CHAM provides important insights into the unmet medical and mental health needs in vulnerable pediatric populations.
Investigators at CHAM are nationally recognized for their cutting edge research leading to advances in:
- vaccine development, prevention of transmission of HIV and other viral and bacterial pathogens
- childhood cancers, including novel therapies for bone tumors and leukemia
- neurologic and behavioral conditions including ADHD, autism, and seizure disorders
- diabetes prevention and treatment, and disorders of bone metabolism
- prevention of preterm birth and its complications, including neonatal lung diseases
- Asthma and obstructive sleep apnea (link – peds pulmonary and general pediatrics research pages
- Sickle Cell Disease.
- Behavioral and mental health conditions
- Conditions impacting adolescents, including medication adherence, transitions to adult care and adolescent AIDS and other sexually transmitted diseases
- Cardiovascular disease and heart failure
- Immune deficiencies and microbiome research
- Rheumatologic conditions, including lupus erythmatosis
- Gastrointestinal conditions including inflammatory bowel disease, fatty liver disease, hepatitis and liver failure
- Pediatric emergency Medicine
- Genetics and epigentics