Trial DescriptionA Long-Term, Open-Label Follow-up Study of Tofacitinib for Treatment of Juvenile Idiopathic Arthritis (JIA) -
Click here for more information15-10-199-01
Disease/ConditionArthritis
Autoimmune Diseases
Musculoskeletal Diseases
Pediatrics
Rheumatic Diseases
Principal InvestigatorDawn Wahezi, MD
Trial DescriptionA Multicenter, Open-label, Randomized, Event-driven Study to Assess Efficacy, Safety and Pharmacokinetics of Macitentan Versus Standard of Care in Children With Pulmonary Arterial Hypertension (PAH) (TOMORROW) -
Click here for more information16-10-366-01
Disease/ConditionHeart and Vascular Diseases
Lung Diseases
Pediatrics
Pulmonary Hypertension
Principal InvestigatorNicole Sutton, MD
Trial DescriptionA Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Ustekinumab in Subjects With Active Systemic Lupus Erythematosus -
Click here for more information18-02-68-01E
Disease/ConditionAutoimmune Diseases
Dermatology
Lupus
Pediatrics
Rheumatic Diseases
Geriatrics
Principal InvestigatorChaim Putterman, MD
Trial DescriptionA Phase 2, Randomized, Double-Blind, Dose-Ranging Study to Determine the Pharmacokinetics, Safety and Tolerability of Vedolizumab IV in Pediatric Subjects With Ulcerative Colitis or Crohn's Disease -
Click here for more information18-10-218-01
Disease/ConditionColitis and Crohn's Disease
Gastroenterology & Liver Diseases
Pediatrics
Inflammatory Bowel Disease
Principal InvestigatorJohn Thompson, MD
Trial DescriptionA Phase 3 Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Hospitalized Patients w/Influenza A Infection -
Click here for more information17-02-306-01
Disease/ConditionGeriatrics
Infectious Diseases
Influenza
Pediatrics
Principal InvestigatorPaul Riska, MD
Trial DescriptionA Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Adolescent and Adult Subjects With Moderate to Severe Atopic Dermatitis -
Click here for more information18-10-220-01
Disease/ConditionDermatology
Pediatrics
Skin Disorders
Geriatrics
Immune System Diseases
Principal InvestigatorHolly Kanavy, MD
Trial DescriptionA Phase 3, Randomized, Open-Label, Multicenter Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD) -
Click here for more information18-10-59-01
Disease/ConditionHematologic Diseases
Kidney Diseases (incl Chronic Kidney Disease)
Metabolic Diseases
Nephrology
Urologic Diseases
Pediatrics
Principal InvestigatorAnna Zolotnitskaya, MD
Trial DescriptionA Phase II Multi-Center, Randomized, Double-Blind, 24-Week, Parallel Group, Placebo-Controlled Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Children and Adolescents Age 5-17 With Autism Spectrum Disorder (ASD) -
Click here for more information16-10-117-01
Disease/ConditionAutism Spectrum Disorder
Neurodevelopmental Disorders
Pediatrics
Psychiatry - Non Cancer
Mental Health and Disorders
Principal InvestigatorEric Hollander, MD
Trial DescriptionA Prospective, Observational, Non-Interventional, Post-Marketing, Patient Registry to Collect Data on Routine Clinical Care in Patients Treated With Cholbam®/Kolbam® (Cholic Acid) -
Click here for more information17-08-442-01
Disease/ConditionGastroenterology & Liver Diseases
Pediatrics
Liver Diseases
Principal InvestigatorNadia Ovchinsky, MD
Trial DescriptionA Randomized, Double-Blind, Placebo-Controlled, Multi-Center Pragmatic Clinical Trial To Evaluate The Effectiveness Of Low Dose Oral Methotrexate In Patients With Pediatric Crohn's Disease Initiating Anti-TNF Therapy (COMBINE) -
Click here for more information2017-7692
Disease/ConditionColitis and Crohn's Disease
Gastroenterology & Liver Diseases
Inflammatory Bowel Disease
Pediatrics
Principal InvestigatorGitit Tomer, MD
Trial DescriptionA Study to Compare Bone Marrow Transplantation to Standard Care in Adolescents and Young Adults With Severe Sickle Cell Disease (BMT CTN #1503) -
Click here for more information2016-6694
Disease/ConditionAnemia
Blood Disorders and Diseases
Sickle Cell
Pediatrics
Genetic Disorders
Hematologic Diseases
Principal InvestigatorCaterina Minniti, MD
Trial DescriptionAn Observational, Multicenter Study of the Prevalence of Cerebrotendinous Xanthomatosis (CTX) in Patient Populations Diagnosed With Early-Onset Idiopathic Bilateral Cataracts -
Click here for more information15-10-432-01
Disease/ConditionGenetic Disorders
Ophthalmic Diseases and Disorders
Pediatrics
Principal InvestigatorNorman Medow, MD
Trial DescriptionARCHIVE: A registry for children with vasculitis: e-entry 08-04-111E
Disease/ConditionHeart and Vascular Diseases
Pediatrics
Rheumatic Diseases
Autoimmune Diseases
Principal InvestigatorMaria Yee, MD
Trial DescriptionAssessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control During Botox Injections for Spasticity Management: A Randomized Control Trial -
Click here for more information2016-6501
Disease/ConditionAnesthesia and Pain Management
Pediatrics
Rehabilitation Medicine
Principal InvestigatorYuxi Chen, MD
Trial DescriptionAutism Genetics Network, Phase II: Increasing Representation of Human Diversity 2012-537
Disease/ConditionAutism Spectrum Disorder
Neurology
Pediatrics
Genetic Disorders
Principal InvestigatorSophie Molholm, PhD
Trial DescriptionBezlotoxumab (MK-6072) Versus Placebo in Children With Clostridium Difficile Infection (CDI) (MK-6072-001) (MODIFY III) -
Click here for more information17-10-212-01
Disease/ConditionImmune System Diseases
Infectious Diseases
Pediatrics
Principal InvestigatorDavid Goldman, MD
Disease/ConditionChild Development
Neurodevelopmental Disorders
Autism Spectrum Disorder
Principal InvestigatorEric Hollander, MD
Disease/ConditionAllergy & Immunology
Allergy and Immune Disorders
Asthma and other Respiratory Diseases
Pediatrics
Principal InvestigatorJonathan Feldman, PhD
Trial DescriptionDefensin and Innate Mucosal Immune Mediator Expression in Pediatric Inflammatory Bowel Disease 2012-529
Disease/ConditionGastroenterology & Liver Diseases
Inflammatory Bowel Disease
Pediatrics
Principal InvestigatorGitit Tomer, MD
Trial DescriptionEfficacy of a Gluten-free Diet in Difficult to Manage Nephrotic Syndrome: Utility of Plasma Zonulin Levels as a Predictive Biomarker -
Click here for more information2017-8362
Disease/ConditionKidney Diseases (incl Chronic Kidney Disease)
Nephrology
Pediatrics
Urologic Diseases
Principal InvestigatorFrederick Kaskel, MD
Disease/ConditionAnemia
Hematologic Diseases
Pediatric Hematology/Oncology
Pediatrics
Genetic Disorders
Principal InvestigatorDeepa Manwani, MD
Disease/ConditionNeonatology
Pediatrics
Overweight, Obesity and Weight Loss
Principal InvestigatorMamta Fuloria, MD
Trial DescriptionMulticenter, Open Label, Phase 3 Study of Tabelecleucel for Solid Organ Transplant Subjects With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE) -
Click here for more information16-10-296-01
Disease/ConditionEpstein-Barr Virus (EBV)
Lymphoproliferative Disorders
Pediatric Hematology/Oncology
Pediatrics
Solid Organ Transplant (SOT) Complications
Immune System Diseases
Principal InvestigatorDavid Loeb, MD
Disease/ConditionGeriatrics
Kidney Diseases (incl Chronic Kidney Disease)
Nephrotic Syndrome
Pediatrics
Urologic Diseases
Immune System Diseases
Principal InvestigatorFrederick Kaskel, MD
Disease/ConditionLung Diseases
Pediatrics
Asthma and other Respiratory Diseases
Principal InvestigatorDeepa Rastogi, MD
Trial DescriptionPhase 2 Study: Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Children and Adolescents With Prader-Willi Syndrome -
Click here for more information2017-8076
Disease/ConditionPsychiatry - Non Cancer
Nervous System Diseases
Child Development
Pediatrics
Genetic Disorders
Principal InvestigatorEric Hollander, MD
Trial DescriptionPhase III Multicenter Open-label Randomized Clinical Trial Comparing Everolimus and Low Dose Tacrolimus to Tacrolimus and Mycophenolate Mofetil at 6 mo Post-Transplant to Prevent Long-term Complications After Pediatric Heart Transplantation -
Click here for more information2017-8626
Disease/ConditionHeart and Vascular Diseases
Kidney Diseases (incl Chronic Kidney Disease)
Pediatrics
Urologic Diseases
Cardiovascular and Thoracic Surgery
Principal InvestigatorJacqueline Lamour, MD
Trial DescriptionPromoting Asthma Guidelines and Management through Technology-Based Intervention and Care Coordination (PRAGMATIC) -
Click here for more information2016-6258
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorMarina Reznik, MD
Trial DescriptionProtocol for a Research Sample Repository and for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies, and Marrow Toxic Injuries -
Click here for more information2015-5698
Disease/ConditionHematologic Diseases
Neoplasms
Pediatric Hematology/Oncology
Pediatrics
Oncology (Medical/Hematologic)
Principal InvestigatorDavid Loeb, MD
Trial DescriptionSelf regulation in children with learning disabilities and inattention/hyperactivity IRB# 2006-425
Disease/ConditionChild Development
Principal InvestigatorKatherine Lawson, PhD
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Orthopaedic Surgery
Pediatrics
Neoplasms
Musculoskeletal Diseases
Principal InvestigatorJacob Schulz, MD
Disease/ConditionHematologic Diseases
Pediatrics
Principal InvestigatorDavid Loeb, MD
Trial DescriptionVALENS: A Ph 1/2, Random'd, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate Safety/Preliminary Efficacy of AT342, an AAV8-Delivered Gene Transfer Therapy in Crigler-Najjar Syndrome Subjects Aged 1 Yr and Older -
Click here for more information2017-7918
Disease/ConditionBrain and Neurological
Crigler-Najjar Syndrome
Gastroenterology & Liver Diseases
Heart and Vascular Diseases
Metabolic Diseases
Pediatrics
Principal InvestigatorNadia Ovchinsky, MD
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorDeepa Rastogi, MD