Banner
Share

Research

In conjunction with the Albert Einstein College of Medicine, the Division of Endocrinology and Diabetes at CHAM participates in a wide range of research from basic science to human clinical trials.

The Division of Endocrinology and Diabetes at CHAM participates in a wide range of research from basic science to human clinical trials In conjunction with Albert Einstein College of Medicine.

Our research includes conducting trials for newly diagnosed diabetes patients and those living with type 1 or type 2 diabetes, polycystic ovarian syndrome or obesity, as well as screening for relatives of type 1 diabetics and much more. We are currently focused on research to:  

Improve the Quality of Life for Children with Diabetes

Through research using the artificial pancreas and drug therapy, CHAM endocrinologists are working to automate mealtime glucose measurement and insulin delivery, and reduce sugar levels in type 1 diabetics. Patients in the current study have not had to worry about frequent glucose checks, and blood sugars remain under control.

Create Better Outcomes for Girls with Turner Syndrome

As a destination of choice for girls born with Turner syndrome, and their families, CHAM’s experts draw upon the hospital’s vast resources—including infertility treatment, diabetes and thyroid management, and orthopaedic surgery—to treat the many health concerns that these patients encounter. CHAM has also partnered with the Turner Syndrome Foundation to host in-depth educational seminars each year.

Discover Alternative Approaches to Nutritional Counseling

Endocrinologists and nutritionists at CHAM are studying whether nutrition and weight-loss counseling provided in a group setting is equally or more beneficial than a one-on-one approach. Each session offers patients and their parents the opportunity to ask questions and interact with other families, thereby building a lasting network of support and providing an effective means through which lower-income families can achieve their health goals.

Prepare for Diabetes Care During Disaster

By surveying patients in the months after Hurricane Sandy, CHAM endocrinologists determined that patients in lower socioeconomic brackets were equally prepared as those who are more affluent for general disasters and diabetes management. These findings differ from results of an earlier survey conducted in Texas and serve to guide CHAM’s future educational efforts.
Research is a great way to get involved, learn more about diabetes, be more involved in your care and help others. 

You can use the information below to learn more about some of our trials.

Active Clinical Trials

Trial Description
Disease / Condition
Principal Investigator
Contact
Trial DescriptionA Long-Term, Open-Label Follow-up Study of Tofacitinib for Treatment of Juvenile Idiopathic Arthritis (JIA) - Click here for more information15-10-339-01
Disease/ConditionRheumatic Diseases
Pediatrics
Arthritis
Musculoskeletal Diseases
Autoimmune Diseases
Principal InvestigatorDawn Wahezi, MD
Contact Marija Dionizovik-Dimanovski

Email Contact
Trial DescriptionA Multicenter Single-arm Extension Study to Characterize the Long-term Safety of Cinacalcet Hydrochloride in the Treatment of Secondary Hyperparathyroidism in Pediatric Subjects With Chronic Kidney Disease on Dialysis - Click here for more informationIRB# 20140159
Disease/ConditionDiabetes and Endocrine
Kidney Diseases (Chronic Kidney Disease)
Principal InvestigatorAnna Zolotnitskaya, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionA Multicenter, Open-label, Randomized, Event-driven Study to Assess Efficacy, Safety and Pharmacokinetics of Macitentan Versus Standard of Care in Children With Pulmonary Arterial Hypertension - Click here for more information16-10-366-01
Disease/ConditionHeart and Vascular Diseases
Pediatrics
Pulmonary Hypertension
Lung Diseases
Principal InvestigatorNicole Sutton, MD
Contact Chelsie Cornelius

Email Contact
Trial DescriptionA Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose Optimization Study to Assess the Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome - Click here for more information17-10-298-01
Disease/ConditionPediatrics
Psychiatry - Non Cancer
Tourette Syndrome
Neurodevelopmental Disorders
Principal InvestigatorEric Hollander, MD
Contact Elisabetta Burchi

Email Contact
Trial DescriptionA Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study of GBT440 Administered Orally to Patients With Sickle Cell Disease - Click here for more information17-02-160Q-01
Disease/ConditionHematologic Diseases
Pediatrics
Sickle Cell
Principal InvestigatorCaterina Minniti, MD
Contact Elena Crouch

Email Contact
Trial DescriptionA PHASE 3, OPEN-LABEL, RANDOMIZED, MULTICENTER, 12 MONTHS, EFFICACY AND SAFETY STUDY OF WEEKLY MOD-4023 COMPARED TO DAILY GENOTROPIN- THERAPY IN PRE-PUBERTAL CHILDREN WITH GROWTH HORMONE DEFICIENCY - Click here for more information16-10-374-01
Disease/ConditionChild Development
Endocrinology
Pediatrics
Principal InvestigatorPing Zhou, MD
Contact Susan Wesoly

Email Contact
Trial DescriptionA Phase II Multi-Center, Randomized, Double-Blind, 24-Week, 3-Arm, Parallel-Group, Placebo-Controlled Study to Investigate the Efficacy and Safety of RO5285119 in Children and Adolescents Age 5-17 with Autism Spectrum Disorder (ASD) - Click here for more information16-10-117-01
Disease/ConditionAutism Spectrum Disorder
Pediatrics
Psychiatry - Non Cancer
Neurodevelopmental Disorders
Principal InvestigatorEric Hollander, MD
Contact Danya Schlussel

Email Contact
Trial DescriptionA Prospective, Observational, Non-Interventional, Post-Marketing, Patient Registry to Collect Data on Routine Clinical Care in Patients Treated with Cholbam/Kolbam (Cholic Acid) - Click here for more information17-08-442-01
Disease/ConditionGastroenterology & Liver Diseases
Pediatrics
Principal InvestigatorNadia Ovchinsky, MD
Contact Sharon Thomas

Email Contact
Trial DescriptionA Rando'd, Double-Blind, Placebo-Cont'd Trial to Evaluate Safety, Tolerability, PK and Efficacy of Single Infusion of Bezlotoxumab (MK-6072, Human Monoclonal Antibody to C.Diff Toxin B) in Children 1 to <18 Yrs Receiving Antibacterial Drug Tx for C.Diff - Click here for more information17-10-212-01
Disease/ConditionInfectious Diseases
Pediatrics
Principal InvestigatorDavid Goldman, MD
Contact Sonia Sheehan

Email Contact
Trial DescriptionA Randomized, Double-Blind, Placebo-Controlled, Multi-Center Pragmatic Clinical Trial To Evaluate The Effectiveness Of Low Dose Oral Methotrexate In Patients With Pediatric Crohn's Disease Initiating Anti-TNF Therapy (COMBINE) - Click here for more information2017-7692
Disease/ConditionGastroenterology & Liver Diseases
Pediatrics
Inflammatory Bowel Disease
Colitis and Crohn's Disease
Principal InvestigatorGitit Tomer, MD
Contact Preeti Malik

Email Contact
Trial DescriptionChildhood Asthma Perception Study (CAPS) - Click here for more information2014-3257
Disease/ConditionAsthma and other Respiratory Diseases
Allergy and Immune Disorders
Allergy & Immunology
Pediatrics
Principal InvestigatorJonathan Feldman, PhD
Contact Jonathan Feldman, PhD

Email Contact
Trial DescriptionNovel Mobile Device Application to Improve Adherence - Click here for more information2016-6359
Disease/ConditionHeart and Vascular Diseases
Cardiology
Cardiovascular and Thoracic Surgery
Pediatrics
Principal InvestigatorJacqueline Lamour, MD
Contact Jacqueline Lamour, MD

Email Contact
Trial DescriptionPeer Mentor Training to Reduce Hospitalizations for Children With Asthma - Click here for more information10-06-174E
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorDeepa Rastogi, MD
Contact Deepa Rastogi, MD

Email Contact
Trial DescriptionPhase 2 Study: Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Children and Adolescents With Prader-Willi Syndrome - Click here for more information2017-8076
Disease/ConditionChild Development
Genetic Disorders
Pediatrics
Psychiatry - Non Cancer
Nervous System Diseases
Principal InvestigatorEric Hollander, MD
Contact Danya Schlussel

Email Contact
Trial DescriptionPromoting Asthma Guidelines and Management through Technology-Based Intervention and Care Coordination (PRAGMATIC) - Click here for more information2016-6258
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorMarina Reznik, MD
Contact Guadalupe Salazar

Email Contact
Trial DescriptionProtocol for a Research Sample Repository and for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies, and Marrow Toxic Injuries - Click here for more information2015-5698
Disease/ConditionHematologic Diseases
Pediatrics
Neoplasms
Principal InvestigatorDavid Loeb, MD
Contact Elodie Benard

Email Contact
Trial DescriptionSimple Bone Cysts in Kids (SBoCK) - Click here for more information2015-4768
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Orthopaedic Surgery
Pediatrics
Musculoskeletal Diseases
Neoplasms
Principal InvestigatorJacob Schulz, MD
Contact Regina Hanstein

Email Contact
Trial DescriptionStudy of Allogeneic EBV-CTLs in EBV-Associated Viremia or Malignancies - Click here for more information16-10-116-01
Disease/ConditionHematologic Diseases
Pediatrics
Principal InvestigatorDavid Loeb, MD
Contact Elodie Benard

Email Contact
Trial DescriptionVALENS: A Ph 1/2, Random'd, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate Safety/Preliminary Efficacy of AT342, an AAV8-Delivered Gene Transfer Therapy in Crigler-Najjar Syndrome Subjects Aged 1 Yr and Older - Click here for more information2017-7918
Disease/ConditionHeart and Vascular Diseases
Brain and Neurological
Gastroenterology & Liver Diseases
Pediatrics
Crigler-Najjar Syndrome
Metabolic Diseases
Principal InvestigatorNadia Ovchinsky, MD
Contact Sharon Thomas

Email Contact
Trial DescriptionWeb-based Peer Mentor Training to Reduce Hospitalizations for Children with Asthma - Click here for more information2014-3962
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorDeepa Rastogi, MD
Contact Toni Tobias

Email Contact
View all Clinical Trials