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Since 1973, the Division is directed by Dr. Arye Rubinstein and has achieved National and International eminence in all aspects of the field including immune deficiencies, AIDS, Infectious diseases associated with immune aberrations, autoimmune disorders in immune diseases, atopic asthma, food and drug allergies and allergic skin disorders.

The Division is dedicated to provide the highest quality of pediatric and adult patient care while at the same time it is conducting cutting-edge biomedical research that affects infants, children, adolescents and adults. The Division is closely interacting with departments of basic sciences and translational research at the Albert Einstein College of Medicine. It integrates the latest scientific and medical advances and is committed to the training of the next generation of allergist and immunologists. The Allergy and Immunological Training Program directed by this Division is reaching out to the Department of Internal Medicine in the training of Internist in the field. The Training Program directed by Dr Rubinstein since 1978 has to its credit the training of over 150 allergist and immunologist in academic and clinical programs in Pediatrics and Medicine throughout the US.

The faculty of the Division occupy prominent roles at the Albert Einstein College of Medicine, are funded by the National Institutes of Health, New York State and New York City Health Departments, private foundations and the pharmaceutical industry. They serve on various national research committees, serve on editorial boards and reviewers for major medical journals.

The Division provides advanced treatment, research and services in multiple areas:

  • Pediatric, adolescent and adult allergy programs.
  • Allergy immunotherapy (allergy shots, monoclonal antibodies) for environmental allergies and insect sting allergies.
  • Asthma Center in collaboration with the pulmonary division.
  • Food allergies.
  • Angioedema Center.
  • Drug allergy testing and desensitization.
  • Center for Clinical Immunology, Immunodeficiency and Autoimmune disorders.
  • Centers for AIDS Research.
  • Pediatric AIDS Center and Bronx Family, Adolescents and Children Consortium.
  • Clinical Trials with new drugs for allergic disorders, asthma, angioedema, primary immunodeficiencies, HIV and autoimmune disorders.
  • NY State screening program for immunodeficiencies in newborns.
  • Community Outreach Programs

The Division is involved in cutting edge treatment modalities for a wide range of allergic and immunologic disorders. Its investigators have been at the forefront of research in primary and acquired immunodeficiencies, allergy, asthma and skin disorders including a center for Angioedema. It is one of a few New York State screening sites for immune deficiencies in newborns. Infants with identified immune deficiencies are referred for early bone marrow and stem cell therapies.
The Division is directing since 1975 the Training Program in Allergy, Asthma and Immunology

The Allergy, Asthma and Immunology Clinical Research Consortium. 

This is a unique clinical research organization comprised of 18 former Pediatric and Internal Medicine Graduates of the Training Program under the Direction of Dr. Arye Rubinstein who practice in NYC, NJ and Connecticut and collaborate in clinical trial programs of new drugs and treatment modalities.

Some Specific Conditions We Treat:

Clinical Immunodeficiency Center

The Clinical Immunology Center at Einstein/Montefiore is one of the largest in the country. It is recognized by the Modell Foundation as one of the Centers of Excellence that deals with all aspects of immune deficiencies including post infection complications, infectious immune aberrations (post Lyme disease, Mycoplasma, Epstein Barr virus and other infections), autoimmune disorders, lymphatic and other cancers related to immune deficiencies.

The Center gets referrals from all Boroughs, from other states and from abroad. It specializes in the diagnosis and cutting edge of multiple immunological disorders.
The Center is also involved in multiple Clinical Trials including intravenous and subcutaneous gammaglobulin, monoclonal antibody therapies, cytokine therapies, enzyme replacement therapies and treatments for angioedema.

The Clinical Immunology Center is also participating in the newly established pediatric and adult Asthma Center at Montefiore Medical Center.

Asthma Center

We are committed to help asthmatic patients become symptom free and maintain normal lung functions. We identify the underlying causes of asthma, eliminate the causes, treat underlying allergies and/or immune abnormalities.
We are linked to the newly established Asthma Center at Montefiore/Einstein that includes experts in allergy, respiratory and in immunology. We are providing allergy care to all patients of all ages and are designated as the experts in allergy and immune evaluation of patients with hard to treat asthma. 


Chronic sinusitis is a challenging and often hard to treat condition. Our approach is multifaceted taking into consideration:

  • Anatomical changes that are evaluated by our designated experts in otolaryngology
  • Allergic conditions that are being evaluated by us concerning environmental allergens that can be eliminated, allergic components requiring immunotherapy and immune aberrations. The Clinical Immunology Center is best equipped to deal with all issues in unison and is a referral center used by pediatricians, internists and otolaryngologists in the 5 Boroughs and Nationally.

Food Allergies

Food allergies are an increasing entity in the US and in other developed countries. It is most frequent in the pediatric age group but spans to all ages. Food allergies have a significant impact on quality of life and may result in skin disorders, asthma, intestinal diseases and may cause life threatening reactions (anaphylaxis).
The faculty has special expertise in this field, evaluating food allergens by blood tests and skin tests as well as by challenge tests. We provide dietetic recommendations and treatment options.

Drug Allergies

Our program provides tests to diagnose reactions to specific drugs by skin testing, blood testing and challenge testing.
We also provide regimen of rapid desensitization that allows the administration of life-saving drugs in patients who are allergic to them. A frequently employed example is the desensitization to aspirin in patients with heart conditions that require daily administration of aspirin. These procedures are done in a strictly supervised outpatient or inpatient setting.

Skin Conditions

These may include irritating itching (pruritus) with/without skin rashes, eczema, hives (urticaria), psoriasis and angioedema.
We evaluate for systemic conditions that may be causative, food allergies, drug allergies, other inflicting agents such as food additives, artificial coloring, spices, laundry chemicals etc.
We have been designated by the National Angioedema Association as a center for angioedema, adisorder with often life-threatening skin and internal organ swellings. Multiple drugs have been tested by us in clinical trials.


The Division provides cutting edge treatment for children, adolescents and adults with HIV infections. It is the first Pediatric AIDS Center in the US and was involved in multiple research initiatives for HIV including immunotherapies, vaccines and anti-HIV drug trials.

Health Home Program 

A New York State Medicaid Care Coordination program, that provides additional medical, mental health and social support services to eligible Medicaid beneficiaries. 


Montefiore Medical Park – 1515 Blondell Avenue, 2nd Floor, Bronx, New York, 10461 
Comprehensive Family Care Center (Adult and Pediatric) 

Medical Arts Pavilion – 3400 Bainbridge Avenue, 2nd Floor, Bronx, New York, 10467 (Adult and Pediatric) 

Allergy and Asthma Practice – 1180 Morris Park Avenue, Bronx, New York, 10461 (Adult and Pediatric) 

Clinical Immunology Center–1180 Morris Park Avenue, Bronx, New York, 10461 

Pediatric Allergy Clinic at the Children’s Hospital at Montefiore (CHAM)–3415 Bainbrdige Avenue, Bronx, New York, 10467 

Cross County Office–1010 Central Park Avenue, Yonkers, New York, 10704 

Jacobi Medical Center, Bldg 5, 3rd Floor, Bronx, New York, 10461 

North Central Bronx Hospital, Bronx, New York, 10467 

Family Immunology Clinic, Montefiore Medical Park–1621 Eastchester Road, Bronx, New York, 10461 

The Children’s Hospital at Montefiore (CHAM)—3415 Bainbridge Avenue at Gunhill Road, Bronx, NY 10467 

Montefiore Medical Center–Weiler Division, Eastchester Road, Bronx, New York, 10461 

Montefiore Medical Center–Moses Division, East 210th Street, Bronx, New York, 10467 

Jacobi Medical Center, Pelham Parkway, Bronx, New York, 10461 

North Central Bronx Hospital, Kossuth Avenue, Bronx, New York, 10467 

Contact information - Allergy/Immunology

Marcy Sedlacek, Ph.D., MPA

Montefiore Medical Center 
Department of Pediatrics-Allergy and Immunology 
1525 Blondell Ave
2nd Floor, Suite 101
Bronx, NY 10461

Phone: 718.405.8530 
Fax: 718.405.8532