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Craniofacial Center

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Research

Leading-Edge Advancements in Craniofacial Care

The Children's Hospital at Montefiore is part of one of the nation's premier academic medical centers, internationally recognized as a leader of science-driven, patient-centered care, research and education. We have pioneered some of the most innovative and exciting techniques and methodology in the past decade.

All of our craniofacial surgeons were involved with the basic research that makes innovative medical treatments and techniques possible. We have a sophisticated knowledge of how advanced treatments can be best used to benefit each individual child. 

Our team has helped thousands of children who were born with craniofacial differences, and those who have suffered craniofacial trauma. We have developed particular expertise through the treatment of more than 8,000 patients with cleft lip and palate, craniosynostosis and other complex conditions.

Improved Craniofacial Technology and Technique

One of the most thrilling developments in craniofacial care has been the techniques of distraction osteogenesis. First used to lengthen short limbs, this technology can now be applied to the bones of the face, including the lower jaw, mid-face and cranium. These new techniques have vastly improved the outcomes we are able to achieve.

Another area where new techniques have been used is in the realm of bone fixation. Because of concerns regarding growth, we no longer use the metal wires, plates and screws that are used in surgeries performed on the skull. These plates were once typically left in place for a child's entire life, and while problems did not generally arise, surgeons were concerned about potential, as-yet-unknown side effects from this treatment method. Small plates and screws have since been developed that actually dissolve after bone healing has occurred.

We are currently conducting research and clinical trials into the genetic pathways that produce craniofacial deformities, in order to eventually prevent them, and when they cannot be avoided, to help physicians better prepare for their occurrence at the time of a child's birth.

 

Active Clinical Trials

Trial Description
Disease / Condition
Principal Investigator
Contact
Trial DescriptionA 12-Month, Open-Label, Repeat-Dose Safety Study of NRL-1 in Epilepsy Subjects - Click here for more information16-10-27-01
Disease/ConditionNeurology
Epilepsy
Seizures
Principal InvestigatorAlexis Boro, MD
Contact Darlene Rozon

Email Contact
Trial DescriptionA 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease (TARGET-IBD) - Click here for more information17-08-399-01
Disease/ConditionGastroenterology & Liver Diseases
Inflammatory Bowel Disease
Colitis and Crohn's Disease
Principal InvestigatorGitit Tomer, MD
Contact Sharon Thomas

Email Contact
Trial DescriptionA 5-year Longitudinal Observational Study of Patients With Nonalcoholic Fatty Liver (NAFL) or Nonalcoholic Steatohepatitis (NASH) - Click here for more information16-10-402-01
Disease/ConditionLiver Diseases
Principal InvestigatorBryan Rudolph, MD
Contact Bryan Rudolph, MD

Email Contact
Trial DescriptionA Long-Term, Open-Label Follow-up Study of Tofacitinib for Treatment of Juvenile Idiopathic Arthritis (JIA) - Click here for more information15-10-339-01
Disease/ConditionRheumatic Diseases
Pediatrics
Arthritis
Musculoskeletal Diseases
Autoimmune Diseases
Principal InvestigatorDawn Wahezi, MD
Contact Marija Dionizovik-Dimanovski

Email Contact
Trial DescriptionA Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications - Click here for more informationIRB# 2014-4194
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionA Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units Manufactured by the National Cord Blood Program and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients - Click here for more informationIRB# 2015-5071
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionA Multicenter Single-arm Extension Study to Characterize the Long-term Safety of Cinacalcet Hydrochloride in the Treatment of Secondary Hyperparathyroidism in Pediatric Subjects With Chronic Kidney Disease on Dialysis - Click here for more informationIRB# 20140159
Disease/ConditionDiabetes and Endocrine
Kidney Diseases (Chronic Kidney Disease)
Principal InvestigatorAnna Zolotnitskaya, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionA Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304 - Click here for more informationIRB# 15-10-122
Disease/Condition -
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionA Multicenter, Open-label, Randomized, Event-driven Study to Assess Efficacy, Safety and Pharmacokinetics of Macitentan Versus Standard of Care in Children With Pulmonary Arterial Hypertension - Click here for more information16-10-366-01
Disease/ConditionHeart and Vascular Diseases
Pediatrics
Pulmonary Hypertension
Lung Diseases
Principal InvestigatorNicole Sutton, MD
Contact Chelsie Cornelius

Email Contact
Trial DescriptionA Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose Optimization Study to Assess the Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome - Click here for more information17-10-298-01
Disease/ConditionPediatrics
Psychiatry - Non Cancer
Tourette Syndrome
Neurodevelopmental Disorders
Principal InvestigatorEric Hollander, MD
Contact Elisabetta Burchi

Email Contact
Trial DescriptionA Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study of GBT440 Administered Orally to Patients With Sickle Cell Disease - Click here for more information17-02-160Q-01
Disease/ConditionHematologic Diseases
Pediatrics
Sickle Cell
Principal InvestigatorCaterina Minniti, MD
Contact Elena Crouch

Email Contact
Trial DescriptionA PHASE 3, OPEN-LABEL, RANDOMIZED, MULTICENTER, 12 MONTHS, EFFICACY AND SAFETY STUDY OF WEEKLY MOD-4023 COMPARED TO DAILY GENOTROPIN- THERAPY IN PRE-PUBERTAL CHILDREN WITH GROWTH HORMONE DEFICIENCY - Click here for more information16-10-374-01
Disease/ConditionChild Development
Endocrinology
Pediatrics
Principal InvestigatorPing Zhou, MD
Contact Susan Wesoly

Email Contact
Trial DescriptionA Phase II Multi-Center, Randomized, Double-Blind, 24-Week, 3-Arm, Parallel-Group, Placebo-Controlled Study to Investigate the Efficacy and Safety of RO5285119 in Children and Adolescents Age 5-17 with Autism Spectrum Disorder (ASD) - Click here for more information16-10-117-01
Disease/ConditionAutism Spectrum Disorder
Pediatrics
Psychiatry - Non Cancer
Neurodevelopmental Disorders
Principal InvestigatorEric Hollander, MD
Contact Danya Schlussel

Email Contact
Trial DescriptionA Prospective, Observational, Non-Interventional, Post-Marketing, Patient Registry to Collect Data on Routine Clinical Care in Patients Treated with Cholbam/Kolbam (Cholic Acid) - Click here for more information17-08-442-01
Disease/ConditionGastroenterology & Liver Diseases
Pediatrics
Principal InvestigatorNadia Ovchinsky, MD
Contact Sharon Thomas

Email Contact
Trial DescriptionA Rando'd, Double-Blind, Placebo-Cont'd Trial to Evaluate Safety, Tolerability, PK and Efficacy of Single Infusion of Bezlotoxumab (MK-6072, Human Monoclonal Antibody to C.Diff Toxin B) in Children 1 to <18 Yrs Receiving Antibacterial Drug Tx for C.Diff - Click here for more information17-10-212-01
Disease/ConditionInfectious Diseases
Pediatrics
Principal InvestigatorDavid Goldman, MD
Contact Sonia Sheehan

Email Contact
Trial DescriptionA Randomized, Double-Blind, Placebo-Controlled, Multi-Center Pragmatic Clinical Trial To Evaluate The Effectiveness Of Low Dose Oral Methotrexate In Patients With Pediatric Crohn's Disease Initiating Anti-TNF Therapy (COMBINE) - Click here for more information2017-7692
Disease/ConditionGastroenterology & Liver Diseases
Pediatrics
Inflammatory Bowel Disease
Colitis and Crohn's Disease
Principal InvestigatorGitit Tomer, MD
Contact Preeti Malik

Email Contact
Trial DescriptionA Safety Extension Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Asthmatic Adults and Adolescents on Inhaled Corticosteroid Plus LABA (BORA) - Click here for more informationIRB# 15-02-209
Disease/ConditionAsthma and other Respiratory Diseases
Principal InvestigatorGolda Hudes, MD
Contact Mydalyn Beronilla
(718) 405-8075
Email Contact
Trial DescriptionA Study to Compare Bone Marrow Transplantation to Standard Care in Adolescents and Young Adults With Severe Sickle Cell Disease (BMT CTN #1503) - Click here for more information2016-6694
Disease/ConditionBlood and Bone Marrow Cancer
Hematologic Diseases
Sickle Cell
Anemia
Principal InvestigatorCaterina Minniti, MD
Contact Kelsey Branch

Email Contact
Trial DescriptionAn Observational Study of Respiratory Syncytial Virus (RSV) Hospitalizations in Preterm Infants (SENTINEL1) - Click here for more informationOCT14-0608B; IRB# 14-10-456-01
Disease/ConditionInfant Care
Principal InvestigatorIona Munjal, MD
Contact Sonia Sheehan
(718) 741-2478
Email Contact
Trial DescriptionARCHIVE: A registry for children with vasculitis: e-entry IRB# 08-04-111E
Disease/ConditionRheumatic Diseases
Principal InvestigatorDawn Wahezi, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionAssessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission - Click here for more informationACCL1033
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionAutism Genetics Network, Phase II: Increasing Representation of Human Diversity IRB# 2012-537
Disease/ConditionAutism Spectrum Disorder
Principal InvestigatorSophie Molholm, PhD
Contact Danielle DeMaio
(718) 862-1860
Email Contact
Trial DescriptionBiomarkers to Predict Neurodevelopmental Outcomes in Very Preterm Infants - Click here for more information2015-4484
Disease/ConditionPreterm Birth
Neonatology
Neurodevelopmental Disorders
Principal InvestigatorMamta Fuloria, MD
Contact Mamta Fuloria, MD

Email Contact
Trial DescriptionBrentuximab Vedotin and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Hodgkin Lymphoma - Click here for more information2015-4877
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 379-6866
Email Contact
Trial DescriptionBrentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma - Click here for more informationAHOD1221
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBrentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma - Click here for more informationANHL12P1
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCaspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy - Click here for more informationACCL0933
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionChemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors - Click here for more information12-08-281
Disease/ConditionBrain Cancer
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionChildhood Asthma Perception Study (CAPS) - Click here for more information2014-3257
Disease/ConditionAsthma and other Respiratory Diseases
Allergy and Immune Disorders
Allergy & Immunology
Pediatrics
Principal InvestigatorJonathan Feldman, PhD
Contact Jonathan Feldman, PhD

Email Contact
Trial DescriptionCollecting and Storing Biological Samples From Patients With Ewing Sarcoma - Click here for more informationIRB# 08-09-335
Disease/ConditionBone Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma - Click here for more informationAALL05B1
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Tissue From Young Patients With Cancer - Click here for more informationABTR04B1
Disease/ConditionCancer and Genetics
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma - Click here for more informationIRB# 06-04-247
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma - Click here for more information1199905158
Disease/ConditionSoft Tissue Sarcoma/Cancer
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCombination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia - Click here for more informationAALL1131
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionConsideration of Pedicle Screw Misplacement on a Per-Patient Basis: Can we Better Delineate Surgical Risk? IRB# 12-07-237E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Rachel Gecelter
(718) 920-7739
Email Contact
Trial DescriptionDefensin and Innate Immunity IRB# 2012-529-000
Disease/Condition -
Principal InvestigatorGitit Tomer, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionDoes Pedicle Morphology Change with Age? IRB# 11-04-158E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Rachel Gecelter
(718) 920-7739
Email Contact
Trial DescriptionFollow-up study of children with early diagnosis of autism spectrum disorder IRB# 2007-546
Disease/ConditionAutism Spectrum Disorder
Principal InvestigatorLisa Shulman, MD
Contact Lisa Shulman, MD
(718) 430-3901
Email Contact
Trial DescriptionGene Discoveries in Subjects with Crohns Disease of African Descent IRB# 13-01-024
Disease/Condition -
Principal InvestigatorGitit Tomer, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionIbrutinib in Combination With Corticosteroids Versus Placebo in Combination With Corticosteroids in Subjects With New Onset Chronic Graft Versus Host Disease (cGVHD) (INTEGRATE) - Click here for more information17-10-17-01
Disease/ConditionGraft Versus Host Disease (GVHD)
Principal InvestigatorOlga Derman, MD
Contact Kailashben Thummar

Email Contact
Trial DescriptionInfantile Spasms Multicenter Database IRB# 13-01-027
Disease/ConditionBrain and Neurological
Principal InvestigatorElissa Yozawitz, MD
Contact Elissa Yozawitz, MD
(718) 920-4378
Email Contact
Trial DescriptionInternational Registry for Severe Chronic Neutropenia - Click here for more informationIRB# 03-01-015E
Disease/ConditionBlood Disorders and Diseases
Principal InvestigatorKerry Morrone, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionIntravenous Gammaglobulin for Sickle Cell Pain Crises - Click here for more informationIRB # 09-06-172
Disease/ConditionAnesthesia and Pain Management
Blood Disorders and Diseases
Principal InvestigatorDeepa Manwani, MD
Contact Karen Ireland
(718) 741-2401
Email Contact
Trial DescriptionMaintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma - Click here for more information10-07-196
Disease/ConditionBrain and Neurological
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionMatched Targeted Therapy (MTT) Recommendation for Patients with Recurrent, Refractory, or High Risk Leukemias - Click here for more information2016-5971
Disease/ConditionBlood Disorders and Diseases
Pediatric Hematology/Oncology
Leukemia
Cancer
Neoplasms
Principal InvestigatorLisa Gennarini, MD
Contact Annette Pedro

Email Contact
Trial DescriptionMetformin in Children With Relapsed or Refractory Solid Tumors - Click here for more information12-05-190
Disease/ConditionSolid Tumor
Principal InvestigatorDaniel Weiser, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionMood disorder and cognitive dysfunction in pediatric lupus IRB# 2000-154
Disease/ConditionRheumatic Diseases
Principal InvestigatorChaim Putterman, MD
Contact Tamar Rubinstein, MD
(718) 741-2459
Email Contact
Trial DescriptionMulticenter Cohort Study To Evaluate Outcomes After Receipt of Targeted Therapy Matched to an Individualized Cancer Therapy (iCat) Recommendations in Children and Young Adults With Solid Tumors: The iCat2, GAIN Consortium Study - Click here for more information2016-7341
Disease/ConditionSolid Tumor
Hematologic Diseases
Pediatric Hematology/Oncology
Cancer
Principal InvestigatorDaniel Weiser, MD
Contact Annette Pedro

Email Contact
Trial DescriptionMulticenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease (IPSG1) - Click here for more informationIRB# 2013-2550
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorEric Fornari, MD
Contact Eric Fornari, MD
(718) 920-7739
Email Contact
Trial DescriptionNeuropsychological and Behavioral Testing in Younger Patients With Cancer - Click here for more information09-04-137E
Disease/ConditionSupportive Cancer Care
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionNon-Interventional Post-Marketing Safety Study on the Long-Term Safety of HYQVIA (Global) - Click here for more informationIRB# 15-02-306
Disease/ConditionAllergy and Immune Disorders
Principal InvestigatorArye Rubinstein, MD
Contact Gayle Kreinik
(718) 405-8530
Email Contact
Trial DescriptionNorth American Pediatric Renal Trials and Collaborative Studies IRB# 02-06-151E
Disease/ConditionKidney Diseases (Chronic Kidney Disease)
Principal InvestigatorMarcela Del Rio, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionNovel Mobile Device Application to Improve Adherence - Click here for more information2016-6359
Disease/ConditionHeart and Vascular Diseases
Cardiology
Cardiovascular and Thoracic Surgery
Pediatrics
Principal InvestigatorJacqueline Lamour, MD
Contact Jacqueline Lamour, MD

Email Contact
Trial DescriptionObservational Study of Pediatric Rheumatic Diseases: The CARRA Registry - Click here for more informationIRB# 2015-5327
Disease/ConditionRheumatic Diseases
Principal InvestigatorYonit Sterba Ruas, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionOutcomes of Neonatal Acute Kidney Injury In Premature Infants - Click here for more information2013-2900
Disease/ConditionKidney Diseases (Chronic Kidney Disease)
Principal InvestigatorMamta Fuloria, MD
Contact Mamta Fuloria, MD
(718) 904-4105
Email Contact
Trial DescriptionPed Cardiac Quality of LIfe IRB# 08-05-162
Disease/ConditionHeart and Vascular Diseases
Principal InvestigatorJacqueline Lamour, MD
Contact Kimberly Beddows
(718) 741-2315
Email Contact
Trial DescriptionPediatric Heart Transplant Study Group IRB# 08-05-166
Disease/ConditionHeart and Vascular Diseases
Principal InvestigatorJacqueline Lamour, MD
Contact Kimberly Beddows
(718) 741-2315
Email Contact
Trial DescriptionPeer Mentor Training to Reduce Hospitalizations for Children With Asthma - Click here for more information10-06-174E
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorDeepa Rastogi, MD
Contact Deepa Rastogi, MD

Email Contact
Trial DescriptionPersonalized Medicine: Pediatric Total Cancer Care™ Protocol 2013-2690
Disease/ConditionSupportive Cancer Care
Principal InvestigatorDaniel Weiser, MD
Contact Annette Pedro
718-741-2356
Email Contact
Trial DescriptionPharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia (EMERALD) - Click here for more information16-10-391-01
Disease/ConditionKidney Diseases (Chronic Kidney Disease)
Principal InvestigatorAnna Zolotnitskaya, MD
Contact Anna Zolotnitskaya, MD

Email Contact
Trial DescriptionPhase 2 Study: Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Children and Adolescents With Prader-Willi Syndrome - Click here for more information2017-8076
Disease/ConditionChild Development
Genetic Disorders
Pediatrics
Psychiatry - Non Cancer
Nervous System Diseases
Principal InvestigatorEric Hollander, MD
Contact Danya Schlussel

Email Contact
Trial DescriptionProject: Every Child for Younger Patients With Cancer - Click here for more information2016-5989
Disease/ConditionCancer and Genetics
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionPromoting Asthma Guidelines and Management through Technology-Based Intervention and Care Coordination (PRAGMATIC) - Click here for more information2016-6258
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorMarina Reznik, MD
Contact Guadalupe Salazar

Email Contact
Trial DescriptionProspective Evaluation of the Duration of Therapy for Thrombosis In Children - Click here for more information2016-6288
Disease/ConditionHeart and Vascular Diseases
Hematologic Diseases
Pediatric Hematology/Oncology
Embolism or Thrombosis
Principal InvestigatorJennifer Davila, MD
Contact Jennifer Davila, MD

Email Contact
Trial DescriptionProtocol for a Research Sample Repository and for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies, and Marrow Toxic Injuries - Click here for more information2015-5698
Disease/ConditionHematologic Diseases
Pediatrics
Neoplasms
Principal InvestigatorDavid Loeb, MD
Contact Elodie Benard

Email Contact
Trial DescriptionProtocol for a Research Sample Repository for Allogeneic Hematopoietic Stem Cell Transplantation IRB# 08-05-155E
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorIra Braunschweig, MD
Contact Karen Fehn
(718) 405-8446
Email Contact
Trial DescriptionQuarenta Semanas: Innovative Intervention in Prenatal Care for Reduction of Prematurity (quarenta) - Click here for more informationIRB# 2014-3022
Disease/ConditionInfant Care
Principal InvestigatorJudy Aschner, MD
Contact Judy Aschner, MD
(718) 741-2499
Email Contact
Trial DescriptionRadiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can be Removed by Surgery (PAZNTIS) - Click here for more information2015-4866
Disease/ConditionSoft Tissue Sarcoma/Cancer
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2338
Email Contact
Trial DescriptionResponse and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma - Click here for more informationANBL1232
Disease/ConditionNeuroblastoma
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionRisk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia - Click here for more informationAALL0932
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionRisk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia - Click here for more informationIRB# 12-01-021
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionSafety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant - Click here for more informationIRB# 15-11-347
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionSelf regulation in children with learning disabilities and inattention/hyperactivity IRB# 2006-425
Disease/ConditionChild Development
Principal InvestigatorKatherine Lawson, PhD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 6275
Email Contact
Trial DescriptionSensory Integration Therapy in Autism: Mechanisms and Effectiveness IRB# 2014-3795
Disease/ConditionAutism Spectrum Disorder
Principal InvestigatorSophie Molholm, PhD
Contact Maya Madzharova
(718) 862-1817
Email Contact
Trial DescriptionSimple Bone Cysts in Kids (SBoCK) - Click here for more information2015-4768
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Orthopaedic Surgery
Pediatrics
Musculoskeletal Diseases
Neoplasms
Principal InvestigatorJacob Schulz, MD
Contact Regina Hanstein

Email Contact
Trial DescriptionSodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy - Click here for more informationBRANY 16-10-228-01
Disease/ConditionSleep-Wake Disorders
Principal InvestigatorMichael Thorpy, MD
Contact Mariana Figuera Losada
(718) 920-2880
Email Contact
Trial DescriptionStudy of Allogeneic EBV-CTLs in EBV-Associated Viremia or Malignancies - Click here for more information16-10-116-01
Disease/ConditionHematologic Diseases
Pediatrics
Principal InvestigatorDavid Loeb, MD
Contact Elodie Benard

Email Contact
Trial DescriptionStudy of Kidney Tumors in Young Patients - Click here for more information08-05-181E
Disease/ConditionKidney Cancer
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionStudy of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia - Click here for more informationIRB# 15-08-314
Disease/ConditionHeart and Vascular Diseases
Principal InvestigatorScott Aydin,MD
Contact Helen Alexander, RN
(718) 741-2678
Email Contact
Trial DescriptionThe Children’s Spine Registry IRB# 2016-6022
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorJaime Gomez, MD
Contact Regina Hanstein
(718) 920-7743
Email Contact
Trial DescriptionThe Chimerix CMX001 Registry - Click here for more informationIRB# 14-06-233-01
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorOlga Derman, MD
Contact Karen Fehn
(718) 405-8446
Email Contact
Trial DescriptionThe Influence of Breakfast on Hormone Responses and Cognitive Performance, as Assessed by CTET in Lean and Obese Adolescent Males - Click here for more information2015-5542
Disease/ConditionOverweight, Obesity and Weight Loss
Pediatric Endocrinology
Metabolic Diseases
Principal InvestigatorLisa Underland, MD
Contact Liset Estanislao

Email Contact
Trial DescriptionThe National Emergency Airway Registry for Children IRB# 2014-3877
Disease/ConditionAsthma and other Respiratory Diseases
Principal InvestigatorMichael Miksa, MD
Contact Michael Miksa, MD
(718) 741-2455
Email Contact
Trial DescriptionThe Reliability of X-Ray Based Evaluation of Pedicle Screw Misplacement in Adolescent Spinal Deformity IRB# 11-04-159E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Stephen Wendolowski
(718) 920-7739
Email Contact
Trial DescriptionThe use of Complementary and Alternative Medicine in Autism IRB# 2007-371
Disease/ConditionAutism Spectrum Disorder
Principal InvestigatorMaria Valicenti-McDermott, MD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 Ext 6275
Email Contact
Trial DescriptionThe use of Virtual Reality Games to Enhance Therapy for Children with Cerebral Palsy. A pilot Study IRB# 2008-347
Disease/ConditionBrain and Neurological
Principal InvestigatorMaria Valicenti-McDermott, MD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 Ext 6275
Email Contact
Trial DescriptionUS-based, Observational, Drug Registry of Opsumit® (Macitentan) New Users in Clinical Practice - Click here for more information14-08-436-01
Disease/ConditionHeart and Vascular Diseases
Principal InvestigatorSandhya Murthy
Contact Roy Park
718-904-3124
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Trial DescriptionVALENS: A Ph 1/2, Random'd, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate Safety/Preliminary Efficacy of AT342, an AAV8-Delivered Gene Transfer Therapy in Crigler-Najjar Syndrome Subjects Aged 1 Yr and Older - Click here for more information2017-7918
Disease/ConditionHeart and Vascular Diseases
Brain and Neurological
Gastroenterology & Liver Diseases
Pediatrics
Crigler-Najjar Syndrome
Metabolic Diseases
Principal InvestigatorNadia Ovchinsky, MD
Contact Sharon Thomas

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Trial DescriptionWeb-based Peer Mentor Training to Reduce Hospitalizations for Children with Asthma - Click here for more information2014-3962
Disease/ConditionAsthma and other Respiratory Diseases
Pediatrics
Lung Diseases
Principal InvestigatorDeepa Rastogi, MD
Contact Toni Tobias

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