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Research

Researchers at the Children’s Hospital at Montefiore have been setting trends in medicine for years through a commitment to scientific research and clinical trials.

Programs like the Comprehensive Epilepsy Center conduct a broad range of investigations that advance our understanding of epilepsy and other neurological disorders.

From bench to bedside, our investigative spectrum pairs technology with a holistic patient-focused approach to better understand the role that genetics play in epilepsy, examine the pathophysiology of seizures, and evaluate new treatments for patients with seizures. Our pediatric neurology research sets trends that advance treatment options.

Active Clinical Trials

Trial Description
Disease / Condition
Principal Investigator
Contact
Trial DescriptionA 12-Month, Open-Label, Repeat-Dose Safety Study of NRL-1 in Epilepsy Subjects - Click here for more information16-10-27-01
Disease/ConditionEpilepsy
Seizures
Neurology
Brain and Neurological
Principal InvestigatorAlexis Boro, MD
Contact Jeanne Gutierrez

Email Contact
Trial DescriptionA Phase II Multi-Center, Randomized, Double-Blind, 24-Week, Parallel Group, Placebo-Controlled Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Children and Adolescents Age 5-17 With Autism Spectrum Disorder (ASD) - Click here for more information16-10-117-01
Disease/ConditionAutism Spectrum Disorder
Neurodevelopmental Disorders
Pediatrics
Psychiatry - Non Cancer
Mental Health and Disorders
Principal InvestigatorEric Hollander, MD
Contact Danya Schlussel

Email Contact
Trial DescriptionAutism Genetics Network, Phase II: Increasing Representation of Human Diversity 2012-537
Disease/ConditionAutism Spectrum Disorder
Neurology
Pediatrics
Genetic Disorders
Principal InvestigatorSophie Molholm, PhD
Contact Danielle DeMaio
(718) 862-1860
Email Contact
Trial DescriptionCannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD) - Click here for more information2017-8538
Disease/ConditionChild Development
Neurodevelopmental Disorders
Autism Spectrum Disorder
Principal InvestigatorEric Hollander, MD
Contact Erin Shanahan

Email Contact
Trial DescriptionInfantile Spasms Multicenter Database IRB# 13-01-027
Disease/ConditionBrain and Neurological
Principal InvestigatorElissa Yozawitz, MD
Contact Elissa Yozawitz, MD
(718) 920-4378
Email Contact
Trial DescriptionMaintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma - Click here for more information10-07-196
Disease/ConditionBrain and Neurological
Principal InvestigatorLisa Gennarini, MD
Contact Joyce Brown

Email Contact
Trial DescriptionThe use of Virtual Reality Games to Enhance Therapy for Children with Cerebral Palsy. A pilot Study IRB# 2008-347
Disease/ConditionBrain and Neurological
Principal InvestigatorMaria Valicenti-McDermott, MD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 Ext 6275
Email Contact
Trial DescriptionVALENS: A Ph 1/2, Random'd, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate Safety/Preliminary Efficacy of AT342, an AAV8-Delivered Gene Transfer Therapy in Crigler-Najjar Syndrome Subjects Aged 1 Yr and Older - Click here for more information2017-7918
Disease/ConditionBrain and Neurological
Crigler-Najjar Syndrome
Gastroenterology & Liver Diseases
Heart and Vascular Diseases
Metabolic Diseases
Pediatrics
Principal InvestigatorNadia Ovchinsky, MD
Contact Sharon Thomas

Email Contact
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