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Research 

CHAM’s Division of Adolescent Medicine is committed to spearheading research on a wide range of medical and psychosocial problems that adolescents face.

 

We are currently conducting research on:

Improving the Health of Severely Obese Teens

CHAM adolescent medicine physicians and nutritionists are working with severely obese teens and their families through the B’N Fit Program to help with weight management and healthy lifestyle behaviors. Evaluation of the B’N Fit Program participants, after six months, indicated significant decreases in rates of weight gain and increases in fruit and vegetable consumption. Participants also increased their level of vigorous physical activity.

Improving Treatment of Vitamin D Deficiency in Adolescents of Color

Through a randomized clinical trial comparing different treatment regimens, CHAM adolescent medicine physicians are exploring ways to treat vitamin D deficiency, which is epidemic in teens of color living in the northern latitudes.

 

We are also examining the many health benefits of vitamin D, beyond the well-known effects on bone metabolism. We have found that two-thirds of our adolescent patients at CHAM are vitamin D deficient, and that for the one-third of our teens who are obese, higher doses or longer treatment than usually recommended is needed.

Long-Acting Reversible Contraception to Prevent Teen Pregnancy

The teen pregnancy rate in the Bronx is 70 percent higher than in the nation as a whole. To address this, our team has established a long-acting reversible contraception service at CHAM that provides and studies long-acting reversible contraception methods, including dermal implants and intrauterine contraception. Our goal is to prevent teen pregnancy by helping high-risk adolescents obtain effective contraception.

 

CHAM adolescent medicine physicians also recruited a group of adolescent girls to follow for six months and evaluate their use of various effective contraception methods. We found that intrauterine contraception, the IUD, was significantly less likely to be discontinued at six months compared with the “pill,” “shot,” “patch” or “ring” methods of hormonal contraception.

Strengthening Community Responses to Youth and HIV

The AAP is part of a national study called Connect to Protect (C2P). C2P and its Bronx coalition aim to reduce HIV/AIDS rates among young women of color through collaborative efforts to impact community programs, policies and social practices. Together with its community partners, the AAP’s C2P Bronx coalition works to design and engage in structural intervention activities to transform the Bronx’s physical and social environment in ways that can, for the long term, curb the spread of HIV among young people.

Trial Description
Disease / Condition
Principal Investigator
Contact
Trial DescriptionA Double Blind, Randomized, Placebo-Controlled Study of CM-AT for the Treatment of Autism in Children With All Levels of Fecal Chymotrypsin (FCT) - Click here for more informationIRB# 14-10-543
Disease/ConditionAutism
Principal InvestigatorEric Hollander, MD
Contact Bonnie Taylor, Ph.D.
(718) 920-2909
Email Contact
Trial DescriptionA Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications - Click here for more informationIRB# 2014-4194
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionA Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units Manufactured by the National Cord Blood Program and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients - Click here for more informationIRB# 2015-5071
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionA Multicenter Single-arm Extension Study to Characterize the Long-term Safety of Cinacalcet Hydrochloride in the Treatment of Secondary Hyperparathyroidism in Pediatric Subjects With Chronic Kidney Disease on Dialysis - Click here for more informationIRB# 20140159
Disease/ConditionDiabetes and Endocrine
Kidney Disease and Transplant
Principal InvestigatorAnna Zolotnitskaya, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionA Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy - Click here for more informationIRB# 14-10-443
Disease/ConditionBrain and Neurological
Sleep-Wake Disorders
Principal InvestigatorMichael Thorpy, MD
Contact Shelby Harris
(718) 920-4841
Email Contact
Trial DescriptionA Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304 - Click here for more informationIRB# 15-10-122
Disease/ConditionInfectious Disease
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionA Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor (NEWBORN-1) - Click here for more informationIRB# 15-10-340
Disease/ConditionWomen`s Health
Principal InvestigatorAshlesha Dayal, MD
Contact Melissa Hudson
(718) 405-8214
Email Contact
Trial DescriptionA Prospective, Multi-center Registry for Patients With Short Bowel Syndrome - Click here for more informationIRB# 2015-5430
Disease/ConditionDigestive and Intestinal
Principal InvestigatorJohn Thompson, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionA Safety Extension Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Asthmatic Adults and Adolescents on Inhaled Corticosteroid Plus LABA (BORA) - Click here for more informationIRB# 15-02-209
Disease/ConditionAsthma and other Respiratory Diseases
Principal InvestigatorGolda Hudes, MD
Contact Mydalyn Beronilla
(718) 405-8075
Email Contact
Trial DescriptionACTH for Frequently Relapsing and Steroid Dependent Nephrotic Syndrome - Click here for more informationIRB# 2014-3512
Disease/ConditionKidney Disease and Transplant
Principal InvestigatorKimberly Reidy, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionActive commuting to school and behavior problems among school-aged children IRB# 2014-4362
Disease/ConditionChild Development
Principal InvestigatorRuth Stein, MD
Contact Mana Mann
(718) 839-7025
Email Contact
Trial DescriptionAcute Kidney Injury in Children with Acute Respiratory Failure IRB# 2014-3464
Disease/ConditionKidney Disease and Transplant
Asthma and other Respiratory Diseases
Principal InvestigatorScott Aydin, MD
Contact Scott Aydin, MD
(718) 741-2343
Email Contact
Trial DescriptionAn Observational Study of Respiratory Syncytial Virus (RSV) Hospitalizations in Preterm Infants (SENTINEL1) - Click here for more informationOCT14-0608B; IRB# 14-10-456-01
Disease/ConditionInfant Care
Infectious Disease
Principal InvestigatorIona Munjal, MD
Contact Sonia Sheehan
(718) 741-2478
Email Contact
Trial DescriptionAn Observational, Multicenter Study of the Prevalence of Cerebrotendinous Xanthomatosis (CTX) in Patient Populations Diagnosed With Early-Onset Idiopathic Bilateral Cataracts - Click here for more informationIRB#
Disease/ConditionEye Disease
Principal InvestigatorNorman Medow, MD
Contact Jose Rosado
(718) 920-5198
Email Contact
Trial DescriptionAnalysis of Clinical and Laboratory Measures in Children with Intestinal Failure at the Children's Hospital at Montefiore IRB# 2013-2270
Disease/ConditionDigestive and Intestinal
Principal InvestigatorJohn Thompson, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionARCHIVE: A registry for children with vasculitis: e-entry IRB# 08-04-111E
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorDawn Wahezi, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionAre children with Autistic Spectrum Disorder diagnosed before 2 years of age different clinically from older children diagnosed after 2 years of age? IRB# 2005-785
Disease/ConditionAutism
Principal InvestigatorMaria Valicenti-McDermott, MD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 Ext 6275
Email Contact
Trial DescriptionAssessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission - Click here for more informationACCL1033
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionAtypcial Hemolytic-Uremic Syndrome (aHUS) Registry - Click here for more informationOCT12-0278; IRB# 12-12-417
Disease/ConditionKidney Disease and Transplant
Principal InvestigatorFrederick Kaskel, MD
Contact Patricia Flynn
(718) 655-1120
Email Contact
Trial DescriptionAutism Genetics Network, Phase II: Increasing Representation of Human Diversity IRB# 2012-537
Disease/ConditionAutism
Principal InvestigatorSophie Molholm, PhD
Contact Danielle DeMaio
(718) 862-1860
Email Contact
Trial DescriptionAzithromycin for Children Hospitalized With Asthma - Click here for more informationIRB# 12-05-187
Disease/ConditionAsthma and other Respiratory Diseases
Principal InvestigatorLindsey Douglas, MD
Contact Lindsey Douglas, MD
(718) 741-2267
Email Contact
Trial DescriptionBiomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma - Click here for more informationIRB# 1200011361
Disease/ConditionNeuroblastoma
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBlinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia - Click here for more informationIRB# 2015-4876
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBlood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas - Click here for more informationALTE11C1
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia - Click here for more informationAAML1031
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBrentuximab Vedotin and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Hodgkin Lymphoma - Click here for more informationIRB# 2015-4877
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBrentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma - Click here for more informationAHOD1221
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionBrentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma - Click here for more informationANHL12P1
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCaspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy - Click here for more informationACCL0933
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCaspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant - Click here for more informationACCL1131
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionChemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma - Click here for more informationIRB# 08-03-057
Disease/ConditionBrain Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionChemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors - Click here for more informationIRB# 12-08-281
Disease/ConditionBrain Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionClinical characterization of the pre-ictal state in the pediatric population: A caretaker's perspective on seizure prediction IRB# 2013-2455
Disease/ConditionBrain and Neurological
Principal InvestigatorSheryl Haut, MD
Contact Puja Patel
(917) 205-7283
Email Contact
Trial DescriptionCollecting and Storing Biological Samples From Patients With Ewing Sarcoma - Click here for more informationIRB# 08-09-335
Disease/ConditionBone Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer - Click here for more informationIRB# 05-03-067
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma - Click here for more informationIRB# 08-09-336E
Disease/ConditionBone Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma - Click here for more informationAALL05B1
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Tissue From Young Patients With Cancer - Click here for more informationABTR04B1
Disease/ConditionCancer and Genetics
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma - Click here for more informationIRB# 06-04-247
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCollecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma - Click here for more informationIRB# 1199905158
Disease/ConditionSoft Tissue Sarcoma/Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCombination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia - Click here for more informationAALL1131
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCombination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-Metastatic Desmoplastic Medulloblastoma - Click here for more informationIRB# 2015-4856
Disease/ConditionBrain Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCombination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma - Click here for more informationIRB# 2015-4871
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionCompared Outcomes of Closed Reduction in the Emergency Room Versus the Operating Room in the Treatment of Pediatric Supracondylar Humerus Fractures IRB# 2014-3775
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorJacob Schulz, MD
Contact Stephen Sylvia
(718) 920-7739
Email Contact
Trial DescriptionComparison of menstrual patterns and ovarian reserve in adolescent girls with systemic lupus erythematosus, juvenile idiopathic arthritis, and girls without chronic illness IRB# 2014-3824
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorDawn Wahezi, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionConsideration of Pedicle Screw Misplacement on a Per-Patient Basis: Can we Better Delineate Surgical Risk? IRB# 12-07-237E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Rachel Gecelter
(718) 920-7739
Email Contact
Trial DescriptionCureGN: Cure Glomerulonephropathy Network IRB# 2014-4254
Disease/ConditionKidney Disease and Transplant
Principal InvestigatorFrederick Kaskel, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionDefensin and Innate Immunity IRB# 2012-529-000
Disease/ConditionDigestive and Intestinal
Principal InvestigatorGitit Tomer, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionDenosumab in Treating Patients With Recurrent or Refractory Osteosarcoma - Click here for more informationIRB# AOST1321
Disease/ConditionBone Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionDinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma - Click here for more informationIRB# AOST1421
Disease/ConditionBone Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionDoes Pedicle Morphology Change with Age? IRB# 11-04-158E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Rachel Gecelter
(718) 920-7739
Email Contact
Trial DescriptionEffect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants - Click here for more informationIRB# 12-07-234
Disease/ConditionInfant Care
Principal InvestigatorMamta Fuloria, MD
Contact Mamta Fuloria, MD
(718) 904-4105
Email Contact
Trial DescriptionEfficacy of Group Attachment Based Intervention for Vulnerable Families - Click here for more informationIRB# 2005-703
Disease/ConditionChild Development
Principal InvestigatorAnne Murphy, PhD
Contact Anne Murphy, PhD
(718) 839-7265
Email Contact
Trial DescriptionEfficacy, Safety And Tolerability Of Tofacitinib For Treatment Of Polyarticular Course Juvenile Idiopathic Arthritis (JIA) In Children And Adolescent Subjects - Click here for more informationIRB# 15-10-199
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorNorman Ilowite, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionElectrophysiologic Indices of Acoustic Processing Deficits Among Childhood Cancer Survivors IRB# 2011-310
Disease/ConditionSupportive Cancer Care
Principal InvestigatorPeter Cole, MD
Contact Janeta Ivanova
(718) 741-2356
Email Contact
Trial DescriptionEnrollment on the Childhood Cancer Research Network (CCRN) of the Children s Oncology Group - Click here for more informationIRB# 07-01-020E
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionEpigenetic and Developmental Effects of In Utero Exposure to Environmental Toxicants - Click here for more informationIRB# 12-12-428
Disease/ConditionInfant Care
Principal InvestigatorMamta Fuloria, MD
Contact Mamta Fuloria, MD
(718) 904-4105
Email Contact
Trial DescriptionEPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures (EPVent2) - Click here for more informationIRB# 2012-268
Disease/ConditionCritical Care
Asthma and other Respiratory Diseases
Principal InvestigatorMichelle Gong, MD
Contact Daniel Ceusters
(718) 920-2956
Email Contact
Trial DescriptionEvaluation of CYP2D6 genetic polymorphisms in a diverse urban population IRB# 2013-284
Disease/ConditionEars, Nose and Throat
Principal InvestigatorTJ Ow, MD
Contact John Bent, MD
(718) 920-7042
Email Contact
Trial DescriptionEvaluation of the Rate of Discordance between Thiopurine Methyltransferase Phenotype and Genotype in Pediatric Patients with Gastrointestinal Disease IRB# 13-01-046
Disease/ConditionDigestive and Intestinal
Principal InvestigatorInna Novak, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionExploring Brain Responses to Affective Images in Mothers with High or Low Adverse Childhood Experiences (Aces) IRB# 2014-3334
Disease/ConditionChild Development
Principal InvestigatorAnne Murphy, PhD
Contact Anne Murphy, PhD
(718) 839-7265
Email Contact
Trial DescriptionFollow-up study of children with early diagnosis of autism spectrum disorder IRB# 2007-546
Disease/ConditionAutism
Principal InvestigatorLisa Shulman, MD
Contact Lisa Shulman, MD
(718) 430-3901
Email Contact
Trial DescriptionGene Discoveries in Subjects with Crohns Disease of African Descent IRB# 13-01-024
Disease/ConditionDigestive and Intestinal
Principal InvestigatorGitit Tomer, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionGlembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma - Click here for more informationIRB# AOST1521
Disease/ConditionBone Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionHeart And Lung Failure - Pediatric INsulin Titration Trial (HALF-PINT) - Click here for more informationIRB# 2013-386-001
Disease/ConditionPediatric Critical Care
Principal InvestigatorShivanand Medar, MD
Contact Shivanand Medar, MD
(718) 741-2491
Email Contact
Trial DescriptionImproving Pediatric Transport to the Children's Hospital at Montefiore IRB# 2014-4034
Disease/ConditionPediatric Critical Care
Principal InvestigatorChhavi Katyal, MD
Contact Chhavi Katyal, MD
(718) 741-2476
Email Contact
Trial DescriptionInfantile Spasms Multicenter Database IRB# 13-01-027
Disease/ConditionBrain and Neurological
Principal InvestigatorElissa Yozawitz, MD
Contact Elissa Yozawitz, MD
(718) 920-4378
Email Contact
Trial DescriptionInternational Registry for Severe Chronic Neutropenia - Click here for more informationIRB# 03-01-015E
Disease/ConditionBlood Disorders and Diseases
Principal InvestigatorKerry Morrone, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionIntravenous Gammaglobulin for Sickle Cell Pain Crises - Click here for more informationIRB # 09-06-172
Disease/ConditionBlood Disorders and Diseases
Anesthesia and Pain
Principal InvestigatorDeepa Manwani, MD
Contact Karen Ireland
(718) 741-2401
Email Contact
Trial DescriptionLevofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation - Click here for more informationIRB# 12-04-136
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionLong Term Safety and Efficacy Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis - Click here for more informationIRB# 16-10-91
Disease/ConditionSkin Disorders
Principal InvestigatorHolly Kanavy, DO
Contact Hannah Hwang
(718) 920-8352
Email Contact
Trial DescriptionLong-Term Clinical and Radiologic Outcomes of Patients Treated At a Single Institution For Slipped Capital Femoral Epiphysis IRB# 2014-3570
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorJacob Schulz, MD
Contact Stephen Sylvia
(718) 920-7739
Email Contact
Trial DescriptionLong-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies - Click here for more informationIRB# 12-11-393
Disease/ConditionSupportive Cancer Care
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionLong-Term Safety Study Of Tofacinib In Patients With Juvenile Idiopathic Arthritis - Click here for more informationIRB# 15-10-339
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorNorman Ilowite, MD
Contact Marija Dionizovik-Dimanovski
(718) 741-2456
Email Contact
Trial DescriptionMaintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma - Click here for more informationIRB# 10-07-196
Disease/ConditionBrain and Neurological
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionMetformin in Children With Relapsed or Refractory Solid Tumors - Click here for more informationIRB# 12-05-190
Disease/ConditionSolid Tumor
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionMifepristone Induction for Fetal Demise (MIFD) - Click here for more informationIRB# 2015-5689
Disease/ConditionWomen`s Health
Principal InvestigatorJessica Atrio, MD
Contact Jessica Atrio, MD
(718) 405-8260
Email Contact
Trial DescriptionMood disorder and cognitive dysfunction in pediatric lupus IRB# 2000-154
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorChaim Putterman, MD
Contact Tamar Rubinstein, MD
(718) 741-2459
Email Contact
Trial DescriptionMulticenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease (IPSG1) - Click here for more informationIRB# 2013-2550
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorEric Fornari, MD
Contact Eric Fornari, MD
(718) 920-7739
Email Contact
Trial DescriptionNatural History Study of the Development of Type 1 Diabetes - Click here for more informationOCT12-0154; IRB# 12-03-115E
Disease/ConditionDiabetes and Endocrine
Principal InvestigatorRubina Heptulla, MD
Contact Rubina Heptulla, MD
(718) 920-5473
Email Contact
Trial DescriptionNephrotic Syndrome Study Network (NEPTUNE) - Click here for more informationIRB# 2013-272
Disease/ConditionKidney Disease and Transplant
Principal InvestigatorFrederick Kaskel, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionNeuropsychological and Behavioral Testing in Younger Patients With Cancer - Click here for more informationIRB# 09-04-137E
Disease/ConditionSupportive Cancer Care
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionNon-Interventional Post-Marketing Safety Study on the Long-Term Safety of HYQVIA (Global) - Click here for more informationIRB# 15-02-306
Disease/ConditionAllergy and Immune Disorders
Principal InvestigatorArye Rubinstein, MD
Contact Gayle Kreinik
(718) 405-8530
Email Contact
Trial DescriptionNorth American Pediatric Renal Trials and Collaborative Studies IRB# 02-06-151E
Disease/ConditionKidney Disease and Transplant
Principal InvestigatorMarcela Del Rio, MD
Contact Patti Flynn
(718) 655-1120
Email Contact
Trial DescriptionObservational Study of Pediatric Rheumatic Diseases: The CARRA Registry - Click here for more informationIRB# 2015-5327
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorYonit Sterba Ruas, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionOutcomes of coronary artery aneurysms after Kawasaki disease:An international multicentre registry IRB# 2014-383
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorNadine Choueiter, MD
Contact Nadine Choueiter, MD
(718) 741-2254
Email Contact
Trial DescriptionOutcomes of Neonatal Acute Kidney Injury In Premature Infants - Click here for more informationIRB# 2013-2900
Disease/ConditionKidney Disease and Transplant
Principal InvestigatorMamta Fuloria, MD
Contact Mamta Fuloria, MD
(718) 904-4105
Email Contact
Trial DescriptionOxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome (OXT-PWS) - Click here for more informationIRB# 14-10-427-01
Disease/ConditionGenetic Disorders
Principal InvestigatorEric Hollander, MD
Contact Bonnie Taylor, Ph.D.
(718) 920-2909
Email Contact
Trial DescriptionParental Understanding of an In-Toeing Gait IRB# 2014-3753
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorJacob Schulz, MD
Contact David Molho
(718) 920-7739
Email Contact
Trial DescriptionPed Cardiac Quality of LIfe IRB# 08-05-162
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorJacqueline Lamour, MD
Contact Kimberly Beddows
(718) 741-2315
Email Contact
Trial DescriptionPediatric Airway Database: An Observational Trial IRB# 08-03-066E
Disease/ConditionEars, Nose and Throat
Principal InvestigatorJohn Bent, MD
Contact John Bent, MD
(718) 920-7042
Email Contact
Trial DescriptionPediatric Appropriate Use Criteria Implementation Project: An Outpatient Echocardiography Quality Initiative IRB# 2014-3463
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorKenan Stern, MD
Contact Kenan Stern, MD
(718) 741-2538
Email Contact
Trial DescriptionPediatric Heart Transplant Study Group IRB# 08-05-166
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorJacqueline Lamour, MD
Contact Kimberly Beddows
(718) 741-2315
Email Contact
Trial DescriptionPediatric Lupus Trial of Belimumab Plus Background Standard Therapy (PLUTO) - Click here for more informationOCT12-0166; IRB# 12-07-231
Disease/ConditionArthritis, Lupus and other Rheumatology Conditions
Principal InvestigatorDawn Wahezi, MD
Contact Marija Dionizovik-Dimanovski
(718) 696-2402
Email Contact
Trial DescriptionPersonalized Medicine: Pediatric Total Cancer Care™ Protocol IRB# 2013-2690
Disease/ConditionSupportive Cancer Care
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionPharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure (RELAX-PEDS-PK) - Click here for more informationIRB# 14-10-230-01
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorDaphne Hsu, MD
Contact Helen Alexander, RN
(718) 741-2678
Email Contact
Trial DescriptionPilot Study of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for Patients with Recurrent Malignant Neuro-Epithelial Tumors or Without Suitable Autologous Hematopoietic Progenitor Cell Availability IRB# 2014-3856
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionPostadenoidectomy analgesic effects of intraoperative intravenous dexamethasone in children IRB# 12-09-330
Disease/ConditionEars, Nose and Throat
Principal InvestigatorNgoc Nguyen, MD
Contact Ngoc Nguyen, MD
(718) 920-2802
Email Contact
Trial DescriptionPrematurity and Respiratory Outcomes Program (PROP) IRB# 2012-354
Disease/ConditionInfant Care
Principal InvestigatorJudy Aschner, MD
Contact Judy Aschner, MD
(718) 741-2499
Email Contact
Trial DescriptionProfiling Actionable Genetic Alterations in Pediatric Tumors: The Children's Hospital at Montefiore Protocol for Screening Pediatric Tumors to Define Genetic Alterations IRB# 2014-3436
Disease/ConditionCancer and Genetics
Principal InvestigatorAdam Levy, MD
Contact Janeta Ivanova
(718) 741-2356
Email Contact
Trial DescriptionProject: Every Child for Younger Patients With Cancer - Click here for more informationIRB# 2016-5989
Disease/ConditionCancer and Genetics
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionProphylactic Antibiotic Regimens in Tumor Surgery (PARITY) - Click here for more informationIRB# 2014-4077
Disease/ConditionBone Cancer
Principal InvestigatorDavid Geller, MD
Contact Janet Tingling

Email Contact
Trial DescriptionProspective Research Database for Pediatric Patients with Spinal Deformity IRB# 11-03-120E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Rachel Gecelter
(718) 920-7739
Email Contact
Trial DescriptionProspective Scoliosis Outcomes Database IRB# 2016-6190
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorJacob Schulz, MD
Contact Regina Hanstein, PhD
(718) 920-7739
Email Contact
Trial DescriptionProtocol For A Research Database For Hematopoietic Stem Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries - Click here for more informationIRB# 08-05-156
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorIra Braunschweig, MD
Contact Karen Fehn
(718) 405-8446
Email Contact
Trial DescriptionProtocol for a Research Sample Repository for Allogeneic Hematopoietic Stem Cell Transplantation IRB# 08-05-155E
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorIra Braunschweig, MD
Contact Karen Fehn
(718) 405-8446
Email Contact
Trial DescriptionQuarenta Semanas: Innovative Intervention in Prenatal Care for Reduction of Prematurity (quarenta) - Click here for more informationIRB# 2014-3022
Disease/ConditionInfant Care
Principal InvestigatorJudy Aschner, MD
Contact Judy Aschner, MD
(718) 741-2499
Email Contact
Trial DescriptionRadiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can be Removed by Surgery (PAZNTIS) - Click here for more informationIRB# 2015-4866
Disease/ConditionSoft Tissue Sarcoma/Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2338
Email Contact
Trial DescriptionRenal Biomarkers in Pediatric Acute Decompensated Heart Failure IRB# 2014-3053
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorScott Aydin, MD
Contact Scott Aydin, MD
(718) 741-2343
Email Contact
Trial DescriptionResponse and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma - Click here for more informationANBL1232
Disease/ConditionNeuroblastoma
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionRetrospective Evaluation of Sedation Efficacy for Magnetic Resonance Imaging in Pediatric Patients: Dexmedetomidine versus Propofol. IRB# 2013-2541
Disease/ConditionAnesthesia and Pain
Principal InvestigatorChhavi Katyal, MD
Contact Chhavi Katyal, MD
(718) 741-2476
Email Contact
Trial DescriptionRisk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia - Click here for more informationAALL0932
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionRisk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia - Click here for more informationIRB# 12-01-021
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionRisk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer - Click here for more informationIRB# 10-04-087
Disease/ConditionLiver Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionSafety Follow-up of Treatment With Remestemcel-L in Pediatric Patients Who Have Failed to Respond to Steroid Treatment for Acute GVHD - Click here for more informationIRB# 15-10-145Q
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionSafety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant - Click here for more informationIRB# 15-11-347
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorKris Mahadeo, MD
Contact Ruth Santizo
(718) 741-2287
Email Contact
Trial DescriptionSelf regulation in children with learning disabilities and inattention/hyperactivity IRB# 2006-425
Disease/ConditionChild Development
Principal InvestigatorKatherine Lawson, PhD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 6275
Email Contact
Trial DescriptionSensory Integration Therapy in Autism: Mechanisms and Effectiveness IRB# 2014-3795
Disease/ConditionAutism
Principal InvestigatorSophie Molholm, PhD
Contact Maya Madzharova
(718) 862-1817
Email Contact
Trial DescriptionShort Bowel Syndrome Research Study for Children Up To 17 Years of Age on Parenteral Nutrition - Click here for more informationIRB# 15-10-239Q
Disease/ConditionDigestive and Intestinal
Principal InvestigatorJohn Thompson, MD
Contact Sharon Thomas
(718) 741-2557
Email Contact
Trial DescriptionStudy of Kidney Tumors in Young Patients - Click here for more informationIRB# 08-05-181E
Disease/ConditionKidney Cancer
Principal InvestigatorJonathan Gill, MD
Contact Joyce Brown
(718) 741-2356
Email Contact
Trial DescriptionStudy of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH) - Click here for more informationIRB# 14-10-499
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorNicole Sutton, MD
Contact Nicole Sutton, MD
(718) 741-2315
Email Contact
Trial DescriptionStudy of Tedizolid Phosphate (TZD) in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012) - Click here for more informationIRB# 14-10-524Q
Disease/ConditionInfectious Disease
Skin Disorders
Principal InvestigatorIona Munjal, MD
Contact Sonia Sheehan
(718) 741-2470
Email Contact
Trial DescriptionStudy of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia - Click here for more informationIRB# 15-08-314
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorScott Aydin,MD
Contact Helen Alexander, RN
(718) 741-2678
Email Contact
Trial DescriptionStudy to Evaluate the Long-term Safety and Tolerability of USL261 in Patients With Seizure Clusters - Click here for more informationOCT11-0108B; IRB# 11-10-322
Disease/ConditionBrain and Neurological
Principal InvestigatorAlexis Boro, MD
Contact Elan Shoulders, MPH
(718) 920-2898
Email Contact
Trial DescriptionStudy to Evaluate the Safety and Efficacy of USL261 (Intranasal Midazolam) in Patients With Seizure Clusters (ARTEMIS1) - Click here for more informationIRB# 11-10-127
Disease/ConditionBrain and Neurological
Principal InvestigatorAlexis Boro, MD
Contact Elan Shoulders
(718) 920-2898
Email Contact
Trial DescriptionStudy to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload - Click here for more informationIRB# 15-02-284
Disease/ConditionBlood Disorders and Diseases
Principal InvestigatorDeepa Manwani, MD
Contact Karen Ireland
(718) 741-2401
Email Contact
Trial DescriptionThe Children’s Spine Registry IRB# 2016-6022
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorJaime Gomez, MD
Contact Regina Hanstein
(718) 920-7743
Email Contact
Trial DescriptionThe Chimerix CMX001 Registry - Click here for more informationIRB# 14-06-233-01
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorOlga Derman, MD
Contact Karen Fehn
(718) 405-8446
Email Contact
Trial DescriptionThe National Emergency Airway Registry for Children IRB# 2014-3877
Disease/ConditionAsthma and other Respiratory Diseases
Principal InvestigatorMichael Miksa, MD
Contact Michael Miksa, MD
(718) 741-2455
Email Contact
Trial DescriptionThe Pediatric Diabetes Consortium (PDC): Type 2 Diabetes in Youth Registry IRB# 2015-5480
Disease/ConditionDiabetes and Endocrine
Principal InvestigatorRubina Heptulla, MD
Contact Doreen Johnson-Newell
(718) 920-4664
Email Contact
Trial DescriptionThe Reliability of X-Ray Based Evaluation of Pedicle Screw Misplacement in Adolescent Spinal Deformity IRB# 11-04-159E
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Stephen Wendolowski
(718) 920-7739
Email Contact
Trial DescriptionThe Serial Neurocognitive Screening of Children and Adolescents During Treatment for Acute Lymphoblastic Leukemia (ALL) on the Dan Farber Cancer Institute ALL Consortium Study 11-001 IRB# 2013-2140
Disease/ConditionBlood and Bone Marrow Cancer
Principal InvestigatorPeter Cole, MD
Contact Janeta Ivanova
(718) 741-2356
Email Contact
Trial DescriptionThe use of Complementary and Alternative Medicine in Autism IRB# 2007-371
Disease/ConditionAutism
Principal InvestigatorMaria Valicenti-McDermott, MD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 Ext 6275
Email Contact
Trial DescriptionThe use of Virtual Reality Games to Enhance Therapy for Children with Cerebral Palsy. A pilot Study IRB# 2008-347
Disease/ConditionBrain and Neurological
Principal InvestigatorMaria Valicenti-McDermott, MD
Contact Maria Valicenti-McDermott, MD
(718) 430-8600 Ext 6275
Email Contact
Trial DescriptionUS-based, Observational, Drug Registry of Opsumit® (Macitentan) New Users in Clinical Practice - Click here for more informationIRB# 14-08-436-01
Disease/ConditionHeart and Vascular Disease
Principal InvestigatorAli Zaidi, MD
Contact Sandy Congal
(718) 920-2077
Email Contact
Trial DescriptionVertical Expandable Prosthetic Titanium Rib (VEPTR) - (Humanitarian Project) IRB# 12-11-376
Disease/ConditionBones, Muscles & Joints (Orthopaedics)
Principal InvestigatorVishal Sarwahi, MD
Contact Rachel Gecelter
(718) 920-7739
Email Contact
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